Chinese Journal of Contemporary Neurology and Neurosurgery ›› 2016, Vol. 16 ›› Issue (4): 194-196. doi: 10.3969/j.issn.1672-6731.2016.04.004

Previous Articles     Next Articles

Research progress of biological behavior of spinal chordoma in motion segment

LIN Yan-da, WANG Xing-wen, JIAN Feng-zeng   

  1. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Online:2016-04-25 Published:2016-04-15
  • Contact: JIAN Feng-zeng (Email: fengzengjian@hotmail.com)

活动节段脊柱脊索瘤生物学行为研究进展

林彦达, 王兴文, 菅凤增   

  1. 100053 北京,首都医科大学宣武医院神经外科
  • 通讯作者: 菅凤增(Email:fengzengjian@hotmail.com)

Abstract:

Chordomas are low-grade malignant bone tumors that arise from remnants of notochord or aberrant chordal tissue, and have a predilection for the axial skeleton. They are easily recurrent, locally invasive, and have a poor prognosis. Chordomas are also not sensitive to chemotherapy or radiotherapy. Due to the special anatomy of spine, chordomas of mobile spine have their own characteristics. Therefore, this paper reviewed relevant literatures of recent 10 years and summarized the characteristics of biological behavior of mobile spine chordoma, so as to provide new ideas for treating chordoma.

Key words: Chordoma, Spine, Biology, Neurosurgical procedures, Review

摘要:

脊索瘤是临床少见的原发性低度恶性骨肿瘤,源自残留的胚胎脊索或迷走的脊索组织,好发于中轴骨,具有局部侵袭性、复发率高、预后差,以及对放射治疗和药物化疗不敏感等特点,使其临床治疗存在巨大挑战。位于活动节段的脊柱脊索瘤由于脊柱特有的解剖学特点而具有其独特特点,本文通过回顾近年国内外相关文献,对脊索瘤生物学行为特点进行概述,以期为脊索瘤治疗提供新的思路。

关键词: 脊索瘤, 脊柱, 生物学, 神经外科手术, 综述