Abstract: Parkinson's disease (PD), a common neurodegenerative disease in the elderly, is a complex disorder with motor impairment and non-motor manifestations that result in progressive disability and severe complications that have a significant impact on patients' quality of life (QoL). Most of the available QoL instruments depend on written questionnaires. In this review, current possibilities of evaluation of QoL in Parkinson's disease have been critically presented, including universal questionnaires of QoL and the specific ones. The various non-motor symptoms significantly affect patients' QoL. Because of that, instruments for the assessment of depression, anxiety, cognitive dysfunction, sleep disorders and fatigue in Parkinson's disease were also described.

Key words: Parkinson disease, Quality of life, Questionnaires, Review

摘要： 帕金森病是中老年人常见的神经变性疾病，临床表现包括运动症状和非运动症状，缓慢进展，严重影响患者生活质量。目前对帕金森病患者生活质量的评价主要依靠量表。本文拟就帕金森病生活质量问卷之通用量表和专用量表，以及显著影响生活质量的帕金森病非运动症状如抑郁和焦虑、认知功能障碍、睡眠障碍和疲劳相关量表进行概述，并对其进行简要评价。

关键词: 帕金森病, 生活质量, 问卷调查, 综述