Abstract: Alzheimer's disease is the most common cause of dementia in the current elderly population. PET can detect pathophysiological changes in Alzheimer's disease with different radiotracers. This paper will focus on evaluating the value of ¹⁸F-FDG, amyloid and tau protein PET imaging in Alzheimer's disease. PET has been demonstrated to play an important role in the research of etiology, early diagnosis, differential dignosis, prognosis and medical treatment of Alzheimer's disease.

Key words: Positron-emission tomography, Alzheimer disease, Review

摘要： 阿尔茨海默病是老年期痴呆之临床常见类型，随着发病率的逐年升高，受到社会各界更多的关注。PET 功能显像可通过各种显像剂敏感、特异性地反映阿尔茨海默病的病理生理学改变，笔者将重点介绍¹⁸F-FDG 显像剂、淀粉样蛋白和神经原纤维缠结tau 蛋白显像剂在阿尔茨海默病中的应用，详细阐述PET 显像在阿尔茨海默病病因学研究、早期诊断、鉴别诊断、疾病转归和药物治疗中的作用。

关键词: 正电子发射断层显像术, 阿尔茨海默病, 综述