The significance of human brain banking construction for Alzheimer's disease research

doi:10.3969/j.issn.1672-6731.2021.04.004

Abstract

Abstract:

Alzheimer's disease (AD) is the major cause leading to loss of brain function in the elderly. Research in AD and related disorders is not only a means to reveal brain function, but also enhances quality of life in the elderly. In the breakthrough knowledge about AD, studies on human brain tissues affected by AD are essential. The human brain bank collects human brain tissues and plays an important role in the disease diagnosis and reveals the pathogenesis of the disease, thus leading to appropriate treatment and prevention strategies. This article elaborates the contributions of human brain banking in the research of AD and related diseases through summarizing scientific research results using human brain tissues published in the international top journals in 2018-2020.

Key words: Alzheimer disease, Human brain bank (not in MeSH), Review

摘要：

阿尔茨海默病是使老年人群丧失脑功能的主要疾病，阿尔茨海默病研究不仅揭示脑功能，而且对提高老年人生活质量具有重要意义。其突破性研究进展离不开以阿尔茨海默病人脑组织为材料进行的直接研究，脑库收集人脑组织样本并作为重要技术平台在神经系统疾病的诊断、治疗、预防中发挥重要作用。本文重点关注2018-2020年在国际顶级期刊发表的人脑组织参与阿尔茨海默病研究的重大成果，展示脑库在神经科学领域相关疾病研究中的意义和价值。

关键词: 阿尔茨海默病, 人脑组织库(非MeSH词), 综述

DU Juan, YANG Qian, MI Shi-xiong, FAN Ping, CUI Hui-xian, HUANG Yue. The significance of human brain banking construction for Alzheimer's disease research[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2021, 21(4): 245-249.

杜鹃, 杨倩, 米世雄, 樊平, 崔慧先, 黄越. 人脑组织库建设对阿尔茨海默病研究的意义[J]. 中国现代神经疾病杂志, 2021, 21(4): 245-249.

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URL: http://journal11.magtechjournal.com/cjcnn/EN/10.3969/j.issn.1672-6731.2021.04.004

http://journal11.magtechjournal.com/cjcnn/EN/Y2021/V21/I4/245

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