Diagnosis and treatment of pineal region tumors

doi:10.3969/j.issn.1672-6731.2020.04.002

Abstract

Abstract:

Indiscriminate neuroendoscopic biopsy of pineal region tumors is not advisable. For germ cell tumors with elevated tumor markers (β-human chorionic gonadotropin and alpha-fetoprotein), biopsy is not necessary, and neoadjuvant chemotherapy can be used for stratified management. If diagnosis of germ cell tumors is clinically highly suggestive, neuroendoscopic biopsy or diagnostic chemotherapy may be recommended. Except for those two types of the pineal tumors, others can be removed by craniotomy, followed by radiotherapy and chemotherapy according to the pathological results or only followed up.

Key words: Pineal region tumors (not in MeSH), Chemoradiotherapy, Neurosurgical procedures, Review

摘要：

对于松果体区肿瘤的患者，不提倡未加选择、未加甄别地施行神经内镜下肿瘤组织活检术。即使是血清肿瘤标志物β-绒毛膜促性腺激素和（或）甲胎蛋白水平升高的生殖细胞肿瘤病例，亦不建议行肿瘤组织活检术，而是建议采取新辅助化疗进行分层管理。对临床表现高度提示可能是生殖细胞瘤的患者，是神经内镜下肿瘤组织活检术的适应证，但也可采取诊断性药物化疗，或诊断性放射治疗的方案。除上述两类肿瘤外，其他类型的松果体区肿瘤均应先行开颅手术切除肿瘤，然后根据组织病理学结果辅以放化疗或随访观察。

关键词: 松果体区肿瘤（非MeSH词）, 化放疗, 神经外科手术, 综述

FANG Lu-xiong, SONG Ye, QI Song-tao. Diagnosis and treatment of pineal region tumors[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2020, 20(4): 255-257.

方陆雄, 宋烨, 漆松涛. 松果体区肿瘤诊断与治疗策略[J]. 中国现代神经疾病杂志, 2020, 20(4): 255-257.

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URL: http://journal11.magtechjournal.com/cjcnn/EN/10.3969/j.issn.1672-6731.2020.04.002

http://journal11.magtechjournal.com/cjcnn/EN/Y2020/V20/I4/255

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