Abstract:

In view of a variety of cardiovascular events complicated by acute ischemic stroke, the importance of monitoring myocardial ischemic symptoms and signs, electrocardiogram, echocardiogram and myocardial injury markers has been gradually recognized by clinicians. Cardiac troponin (cTn) by conventional assay has been a unique marker of myocardial injury for its extremely high specificity. However, with the utilization of high-sensitivity cardiac troponin (hs-cTn), cTn is no longer exclusive of a disease, but was given more significance in the diagnosis and application value. Therefore, we described the clinical significance of alterations of serum hs-cTn concentration after ischemic stroke.

Key words: Stroke, Brain ischemia, Troponin, Review

摘要：

急性缺血性卒中易并发各种心血管事件，心肌缺血症状与体征、心电图、超声心动图、心肌损伤生物学标志物等的重要性已逐渐为临床医师所接受。传统肌钙蛋白检测以其极高的特异性成为心肌损伤的生物学标志物，然而随着高敏肌钙蛋白的广泛应用，肌钙蛋白已不再专属于某一种疾病，而是赋予更多的诊断意义。本文拟对缺血性卒中后血清高敏肌钙蛋白表达变化的临床意义予以阐述。

关键词: 卒中, 脑缺血, 肌钙蛋白, 综述