Abstract:

This paper analyzed clinical data of 6 patients with central pontine myelinolysis (CPM). Among them 4 cases were male, 2 cases were female, with age 24 to 55 years old and average age 36 years old. Serious somatic diseases occured in all 6 cases. The main clinical manifestations included disturbance of consciousness, pseudobulbar paralysis and flaccid paralysis. Cranial MRI showed all of the patients appeared symmetrical lesions in central pontine. After intravenous drip of glucocorticoids, 5 patients were improved. 

Key words: Myelinolysis, central pontine, Glucocorticoids, Drug therapy

摘要：

回顾分析6 例脑桥中央髓鞘溶解症患者的临床资料，6 例患者中男性4 例，女性2 例；年龄24 ~ 55 岁，平均36 岁；均存在严重躯体疾病，临床表现以意识障碍、假性延髓麻痹、肢体迟缓性瘫痪为主；头部MRI均显示脑桥中央对称性病灶；5例予糖皮质激素冲击治疗，症状有所好转。

关键词: 髓鞘溶解, 中心性脑桥, 糖皮质激素类, 药物疗法