中国现代神经疾病杂志 ›› 2018, Vol. 18 ›› Issue (9): 674-677. doi: 10.3969/j.issn.1672-6731.2018.09.009

• 神经病理性疼痛 • 上一篇    下一篇

2 带状疱疹后神经痛三种治疗方法对比分析

夏焱志, 查俊, 陈洁梅, 乔世刚, 李华, 王琛, 李顺   

  1. 215153 南京医科大学附属苏州医院 苏州科技城医院麻醉及围手术期医学科(夏焱志,查俊,陈洁梅,乔世刚,李华,王琛);310014 杭州,浙江省人民医院疼痛科(李顺)
  • 出版日期:2018-09-25 发布日期:2018-10-12
  • 通讯作者: 查俊(Email:847576705@qq.com)

Clinical study on three treatment methods of postherpetic neuralgia

XIA Yan-zhi1, ZHA Jun1, CHEN Jie-mei1, QIAO Shi-gang1, LI Hua1, WANG Chen1, LI Shun2   

  1. 1Department of Anesthesiology and Perioperative Medicine, Suzhou Hospital Affiliated to Nanjing Medical University; Suzhou Science and Technology Town Hospital, Suzhou 215153, Jiangsu, China
    2Department of Pain, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang, China
  • Online:2018-09-25 Published:2018-10-12
  • Contact: ZHA Jun (Email: 847576705@qq.com)

摘要:

目的 探讨针刺触发点治疗、硬膜外神经阻滞术和选择性背根神经节脉冲射频术3 种方法治疗带状疱疹后神经痛的临床疗效。方法 共60 例带状疱疹后神经痛患者随机分为3 组,分别予针刺触发点治疗(20 例)、硬膜外神经阻滞术(20 例)和选择性背根神经节脉冲射频术(20 例),治疗后均服用加巴喷丁,分别于治疗前和治疗后2、4、12 周采用数字评价量表(NRS)评价疼痛程度。结果 与治疗前相比,3 组患者治疗后2、4 和12 周NRS 评分均降低(均P = 0.000)。治疗后2 周,神经阻滞术组和脉冲射频术组NRS 评分均低于针刺触发点组(P = 0.013,0.000),脉冲射频术组NRS 评分亦低于神经阻滞术(P = 0.000);至治疗后4 和12 周,脉冲射频术组NRS 评分仍低于针刺触发点组(P = 0.000,0.000)和神经阻滞术组(P = 0.000,0.000)。结论 选择性背根神经节脉冲射频术治疗带状疱疹后神经痛效果最佳,可以迅速缓解疼痛,改善患者工作和生活质量。

关键词: 神经痛, 带状疱疹后, 针刺镇痛, 神经传导阻滞, 脉冲射频(非MeSH 词)

Abstract:

Objective  To observe the clinical efficacy of acupuncture trigger point, nerve block and pulse radiofrequency in the treatment of postherpetic neuralgia (PHN). Methods  A total of 60 cases with PHN were randomly divided into 3 groups: acupuncture trigger point therapy (group A, N = 20), epidural nerve block (group B, N = 20) and selective dorsal root ganglion (DRG) pulse radiofrequency (group C, N = 20). All patients in 3 groups took gabapentin orally at the same time after treatment. Numerical Rating Scale (NRS) was used to record the degree of pain in 3 groups before and after treatment (2, 4 and 12 weeks after operation).  Results  Compared with before treatment, NRS scores in 3 groups were significanthly decreased at 2, 4 and 12 weeks after operation (P = 0.000, for all). There was no significant difference on NRS scores among 3 groups before treatment (P > 0.05, for all). Two weeks after operation, NRS scores in group B and C were significantly lower than that in group A (P = 0.013, 0.000), and NRS score in group C was significantly lower than that in group B (P = 0.000). Up to 4 and 12 weeks after operation, NRS score in group C was significantly lower than that in group A (P = 0.000, 0.000) and B (P = 0.000, 0.000), while there was no significant difference on NRS scores between group A and B (P > 0.05).  Conclusions  Selective dorsal root ganglion pulse radiofrequency is effective in the treatment of PHN, which can relieve the pain quickly and improve the work and life quality of patients.

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