中国现代神经疾病杂志 ›› 2015, Vol. 15 ›› Issue (12): 990-993. doi: 10.3969/j.issn.1672-6731.2015.12.014

• 临床研究 • 上一篇    下一篇

2 急性运动轴索性神经病临床分析

李洁颖, 陈海, 董会卿, 贾建平, 易洋   

  1. 100053 北京,首都医科大学宣武医院神经内科[李洁颖(现在贵州省贵阳市第二人民医院神经内科,邮政编码:550081),陈海,董会卿,贾建平];550005 贵阳,武警贵州总队医院眩晕研究所(易洋)
  • 出版日期:2015-12-25 发布日期:2015-12-04
  • 通讯作者: 陈海(Email:chenhai194@sina.com)

Clinical features and treatment of acute motor axonal neuropathy

LI Jie-ying1, CHEN Hai1, DONG Hui-qing1, JIA Jian-ping1, YI Yang2   

  1. 1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China ; 2Institute of Vertigo, the General Hospital of Guizhou Armed Police Forces, Guiyang 550005, Guizhou, China
  • Online:2015-12-25 Published:2015-12-04
  • Contact: CHEN Hai (Email: chenhai194@sina.com)

摘要:

分析9 例急性运动轴索性神经病患者临床特征与治疗方法。对9 例急性运动轴索性神经病患者前驱感染症状、临床表现、神经电生理学检查、治疗原则及出院时神经系统损害恢复评分进行分析,腹泻为其常见前驱感染,并迅速出现四肢瘫痪、肌肉萎缩,病情进展迅速;静脉注射免疫球蛋白辅助甲泼尼龙冲击治疗有效。早期诊断、及时予以免疫治疗对改善患者预后至关重要。

关键词: 格林-巴利综合征, 电生理学, 免疫疗法

Abstract:

This paper aims to investigate the clinical features and treatment of patients with acutemotor axonal neuropathy (AMAN). The clinical data of 9 patients with AMAN treated in our hospital were retrospectively analyzed from prodromal infections, clinical features, neuroelectrophysiological examination, treatment and the scores of Hughes functional grading scale. Diarrhea was the most common prodromal infection, and weakness of four limbs and muscles atrophy acutely emerged. The patient's condition progressed rapidly. In these cases, therapy of immunoglobulin combined with methylprednisolone was effective. Therefore, early diagnosis and timely treating with immunoglobulin therapy are most important methods to improve the prognosis.

Key words: Guillain-Barre syndrome, Electrophysiology, Immunotherapy