中国现代神经疾病杂志 ›› 2015, Vol. 15 ›› Issue (1): 66-66. doi: 10.3969/j.issn.1672-6731.2015.01.020

• 读者作者编者 • 上一篇    下一篇

2 更正:干扰素-β治疗复发-缓解型多发性硬化系统评价

贺电   

  1. 550004 贵阳医学院附属医院神经内科
  • 出版日期:2015-01-25 发布日期:2015-01-20
  • 通讯作者: 贺电 (Email:ileks@163.com)

Erratum to Interferon-beta for relapsing-remitting multiple sclerosis: a systematic review

HE Dian   

  1. Department of Neurology, Affiliated Hospital of Guiyang Medical College, Guiyang 550004, Guizhou, China
  • Online:2015-01-25 Published:2015-01-20
  • Contact: HE Dian (Email: ileks@163.com)

摘要: 由于作者本人疏忽,在统计过程中将率比(RR)自然对数的标准误输入错误,导致干扰素-β(IFN-β)治疗后年复发率的假阴性结果。特申请将我刊2014 年第14 卷第9 期“干扰素-β治疗复发-缓解型多发性硬化系统评价”[1]一文第775 页中文摘要第17 行“但在年复发率方面,INF-β治疗无效。”改为“此外,还显示出INF-β在降低年复发率方面的疗效。”,第776 页英文摘要第20 行“However, the pooled results showed no treatment effect on the annualized relapse rate.”改为“In addition, Meta-analysis showed a treatment effect of IFN-β in reducing the annualized relapse rate.”。将第782 页左栏第13 行“有3 项临床试验(1457 例占68.44%)报告了随访1年时的年复发率[44-46],合并的RR 为0.720(95%CI:0.120 ~ 4.240,P = 0.710;图4a);3项临床试验(919例占43.17%)报告随访2 年时的年复发率[41-43],合并的RR 为0.690(95%CI:0.130 ~ 3.680,P = 0.670;图4b),均显示IFN-β治疗无效。”改为“有3 项临床试验(1457 例占68.44%)报告了随访1 年时的年复发率[44-46],合并的RR 为0.690(95%CI:0.600 ~ 0.790,P = 0.000;图4a);3 项临床试验(919 例占43.17%)报告随访2 年时的年复发率[41-43],合并的RR 为0.680(95%CI:0.610 ~ 0.770,P = 0.000;图4b),均显示出IFN-β在降低年复发率方面的疗效。”,特此更正。

Abstract: The standard errors of the natural log rate ratio (RR) were incorrectly input during the statistical process, leading to false-negative treatment results of interferon-beta (IFN-β) on annualized relapse rate. The corrected statistical data showed that high-dose IFN-β significantly reduced annualized relapse rate at one year or two years of follow-up (RR = 0.690, 95%CI 0.600 to 0.790, P = 0.000, Figure 4a, and RR = 0.680, 95%CI 0.610 to 0.770, P = 0.000, Figure 4b, respectively).