摘要： 采用N-back 神经心理学测试方法对诊断明确的23 例偏头痛患者进行工作记忆能力评价，并与性别、年龄、受教育程度和神经心理学量表评分等相匹配的25 例正常对照者进行比较。结果显示，与正常对照组相比，偏头痛组患者处理工作记忆初级任务时，准确率较高（t = 2.627，P = 0.017），但反应时间延长（t = 1.483，P = 0.012）；而两组受试者处理高级任务时准确率和反应时间差异均无统计学意义（1-back：准确率t = 1.399、P = 0.387，反应时间t = 1.069、P = 0.335；2-back：准确率t = 0.016、P = 0.209，反应时间t = 3.736、P = 0.777）。表明偏头痛患者工作记忆能力总体上与正常人群大致相同。

关键词: 偏头痛, 记忆, 认知障碍, 神经心理学测验

Abstract: In order to explore whether working memory capacity of migraineurs was impaired or not, N-back Test was applied in 23 migraineurs and 25 healthy controls who were matched in sex, age, education, Verbal Fluency Test (VF), Digit Span Test (DS), Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) with migraineurs. It showed that when these migraineurs dealed with primary task of N-back Test (0-back), they showed higher accuracy rate (t = 2.627, P = 0.017) but slower reaction time (t = 1.483, P = 0.012). However, there were no significant differences between 2 groups when they dealed with advanced task of N-back Test (1-back: accuracy rate t = 1.399, P = 0.387, reaction time t = 1.069, P = 0.335; 2-back: accuracy rate t = 0.016, P = 0.209, reaction time t = 3.736, P = 0.777). As a result, working memory capacity of migraineurs was basically matched with healthy controls.

Key words: Migraine disorders, Memory, Cognition disorders, Neuropsychological tests