中国现代神经疾病杂志 ›› 2014, Vol. 14 ›› Issue (1): 21-24. doi: 10.3969/j.issn.1672-6731.2014.01.006

• 颈动脉内膜切除术临床研究 • 上一篇    下一篇

2 高龄颈动脉狭窄患者颈动脉内膜切除术和颈动脉支架成形术的安全性比较

谌燕飞, 宋刚, 凌锋, 郭锋, 张文彬, 华扬, 蔡兵, 焦力群   

  1. 100053 北京,首都医科大学宣武医院神经外科(谌燕飞、宋刚、凌锋、焦力群),血管超声科(华扬),麻醉科(蔡兵);276000 山东省临沂市人民医院神经外科(郭锋);271600 山东省肥城市人民医院神经外科(张文彬)
    谌燕飞、宋刚同为第一作者
  • 出版日期:2014-01-25 发布日期:2014-01-24
  • 通讯作者: 焦力群 (Email:jiaoliqun@gmail.com)
  • 基金资助:

    国家“十二五”科技支撑计划项目(项目编号:2011BAI08B04)

Comparison between outcomes of carotid endarterectomy and carotid artery stenting in treating elderly patients

CHEN Yan-fei1, SONG Gang1, LING Feng1, GUO Feng2, ZHANG Wen-bin3, HUA Yang4, CAI Bing5, JIAO Li-qun1   

  1. 1Department of Neurosurgery, 4Department of Vascular Ultrasound, 5Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
    2Department of Neurosurgery, Linyi People's Hospital, Linyi 276000, Shandong, China
    3Department of Neurosurgery, Feicheng People's Hospital, Feicheng 271600, Shandong, China
  • Online:2014-01-25 Published:2014-01-24
  • Contact: JIAO Li-qun (Email: jiaoliqun@gmail.com)
  • Supported by:

    This study was supported by National "Twelfth Five-Year" for Science and Technology Support Program (No. 2011BAI08B04).

摘要: 手术视频点击进入 目的 回顾接受颈动脉内膜切除术和颈动脉支架成形术的高龄(≥ 70 岁)颈动脉狭窄患者的临床资料,分析手术安全性。方法 共691 例颈动脉狭窄患者,121 例行颈动脉内膜切除术、570 例行颈动脉支架成形术,分析两组患者危险因素、临床特征和术后并发症发生率,评价两种手术方法之安全性。结果 术后30 d 时,两组患者病死率(0.83%对1.05%,P = 1.000)、脑卒中(4.13%对1.93%,P =0.258)和心肌梗死(0.83%对0,P = 0.175)发生率差异均无统计学意义;但颈动脉内膜切除术组患者术后心脏不良事件(8.26%对1.05%,P = 0.000)和脑神经损伤(4.96%对0,P = 0.000)发生率高于颈动脉支架成形术组,而窦性心动过缓或低血压发生率低于颈动脉支架成形术组(0对7.54%,P = 0.002)。结论 高龄患者接受颈动脉内膜切除术或颈动脉支架成形术均有较高的安全性,术前应全面评价患者基础情况,以减少术后并发症发生率。

关键词: 颈动脉狭窄, 颈动脉内膜切除术, 支架, 手术后并发症

Abstract: Objective  To review the clinical data of elderly patients treated by carotid endarterectomy (CEA) and carotid artery stenting (CAS), and analyze the safety of two kinds of surgery.  Methods  A total of 691 patients with carotid artery stenosis underwent CEA (121 cases) and CAS (570 cases) respectively. The risk factors, clinical symptoms and postoperative complications in 2 groups of patients were analyzed, and the safety of two kinds of surgery were assessed. Results  After 30 d of operation, no significant difference was found between 2 groups in death rate (0.83% vs 1.05%, P = 1.000), stroke rate (4.13% vs 1.93% , P = 0.258) or myocardial infarction rate (0.83% vs 0, P = 0.175). Heart complications and cranial nerve injury rate in CEA group was significantly higher than that in CAS group (8.26% vs 1.05%, P = 0.000; 4.96% vs 0, P = 0.000), while sinus bradycardia or hypotension rate in CEA group was significantly lower than that in CAS group (0 vs 7.54%, P = 0.002).  Conclusions  Both CEA and CAS are safe for the elderly patients. However, the conditions of elderly patients should be evaluated before operation in order to reduce occurence of complications after operation.

Key words: Carotid stenosis, Endarterectomy, carotid, Stents, Postoperative complications