Abstract: Objective To analyze the characteristics of ventricular repolarization variables based on T-wave morphology and to determine their relationships with age, sex, blood pressure, heart rate and cardiac hypertrophy in an adult population from Heilongjiang province. Methods A total of 2514 subjects (range 35-81years; 43% men) were included. Bazett corrected QT interval (QTcB), Fridericia corrected QT interval (QTcF) and four T-wave morphology parameters total cosine R-to-T(TCRT), T-wave morphology dispersion(TMD), relative T-wave residuum(rTWR) and principle component T-wave analysis ratio(PCA ratio) were used to evaluate the ventricular repolarization. Multivariate regression was used to test for the dependence of T-wave morphology variables with the subject age, sex, systolic blood pressure and Sokolow index. Result All ventricular repolarization variables had significant sex different (P<0.05). All parameters but TCRT were higher in the high blood pressure group (P<0.05). Age, sex and systolic pressure had independent effect on ventricular repolarization variables. Sokolow index only had effect on T-wave morphology variables. Conclusion T-wave morphology variables are quantified marker of ventricular repolarization heterogeneity, which was influenced by age, sex, blood pressure and myocardial hypertrophy.

Key words: electrocardiography, ventricular repolarization, T-wave morphology analysis