Basic & Clinical Medicine ›› 2020, Vol. 40 ›› Issue (11): 1561-1564.

• Mini Reviews • Previous Articles     Next Articles

Research progress of biological clock in regulation of tumor development

GAO Dong-xiao1, LIU Dan1, GUO Qiang2, LUO Ying1*, LIU Jing1*   

  1. 1. Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, Kunming 650500;
    2. Yunnan Provincial Institute of Digestive Disease, the First People's Hospital of Yunnan Province, Kunming 650011, China
  • Received:2019-09-05 Revised:2020-01-03 Online:2020-11-05 Published:2020-10-30
  • Contact: *;

Abstract: Biological clock is a physiological controlling system with self-regulating functions. There is a close relationship between biological clock disorders and the occurrence of tumors, but underlying mechanism has not yet been elucidated. The biological clocks affect the tumorigenesis through cell cycle, proliferation and gene mutations. Exploring the possible mechanism between biological clock and tumorigenesis can provide some potential strategies for tumor treatment and intervention.

Key words: biological clock, tumor, mechanism

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