Basic & Clinical Medicine ›› 2015, Vol. 35 ›› Issue (1): 117-121.
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Abstract: Inflammasomes are multiprotein complexes that can recognize pathogenic microorganisms and stress-associated endogenous molecules and play an important role in innate immune system.Inflammasomes cause inflammatory response by inducing maturation of inflammatory cytokines interleukin(IL)-1β and IL-18 through activation of caspase-1,and involve in the pathogenesis of various diseases such as cryopyrin-associated periodic syndrome、ischemia-reperfusion injury and atherosclerosis.
Key words: inflammasome, NLRP3, IL-1β
CLC Number:
R5
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URL: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/
http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2015/V35/I1/117