The progress in the study of SIRT1 effect on the bone repair of mesenchymal stem cells

Basic & Clinical Medicine ›› 2014, Vol. 34 ›› Issue (12): 1714-1717.

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The progress in the study of SIRT1 effect on the bone repair of mesenchymal stem cells

Na WANG¹, ²

1. Hebei united university affiliated hospital
2.

Received:2014-03-19 Revised:2014-05-25 Online:2014-12-05 Published:2014-11-25

Abstract

Abstract: The activation of SIRT1 can extend the lifetime of cells, postpone the appearance of senium. SIRT1 also plays an important role in the regulation of the inflammatory reaction. In the process of tissue repair based-mesenchymal stem cells, cell aging and inflammation have an critical influence on the repair ability. Therefore, it is hopeful to change MSCs repair ability by modulating the activity of SIRT1.

Key words: mesenchymal stem cells , SIRT1 , senium , inflammation , bone repair

CLC Number:

R336

Na WANG. The progress in the study of SIRT1 effect on the bone repair of mesenchymal stem cells[J]. Basic & Clinical Medicine, 2014, 34(12): 1714-1717.

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The progress in the study of SIRT1 effect on the bone repair of mesenchymal stem cells

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