The biological functions of ACE2-Ang(1-7)-Mas axis and its downstream signaling pathways

Basic & Clinical Medicine ›› 2014, Vol. 34 ›› Issue (12): 1718-1722.

The biological functions of ACE2-Ang(1-7)-Mas axis and its downstream signaling pathways

Received:2013-11-18 Revised:2014-03-24 Online:2014-12-05 Published:2014-11-25

Abstract

Abstract: ACE2-Ang(1-7)-Mas axis antagonistics ACE-AngⅡ-AT1R classic axis in many internal physiological responses ,which plays an important protective role in circulation ,urinary,digestive systems and inflammation response. The biological functions of ACE2-Ang(1-7)-Mas axis is closely related to its signaling pathways. Exploring the biological function of this adjustment axis and its signaling transduction pathways will provide new ideas for related diseases.

Key words: Key words: ACE2-Ang(1-7)-Mas axis, biological function, signaling pathway

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The biological functions of ACE2-Ang(1-7)-Mas axis and its downstream signaling pathways

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