Role of PI3K and Akt in cardiovascular diseases

Basic & Clinical Medicine ›› 2019, Vol. 39 ›› Issue (8): 1200-1204.

Role of PI3K and Akt in cardiovascular diseases

Received:2019-06-12 Revised:2019-06-25 Online:2019-08-05 Published:2019-07-16
Contact: chunmei CAO E-mail:caochunmei@pku.edu.cn

Abstract

Abstract: The PI3K-Akt signaling pathway plays an important role in cell proliferation and metabolism, and the PI3K-Akt signaling pathway plays an important role in cardiac protective mechanisms -- ischemic preconditioning and ischemic postconditioning. In this paper, the effects of PI3K molecule and Akt molecule, as well as PI3K-Akt signaling pathway on cardiac and vascular physiology and pathology were analyzed to understand its role in cardiovascular diseases.

Key words: PI3K, Akt, Acute myocardial infarction, Cardiovascular disease

CLC Number:

R331.3

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Role of PI3K and Akt in cardiovascular diseases

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