Basic & Clinical Medicine ›› 2017, Vol. 37 ›› Issue (3): 405-409.
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Abstract: Autophagy is a biological process which cells maintain homeostasis through degradation of cytoplasmic macromolecules and damaged organelles by membrane vesicle structure. Autophagy plays a critical role in maintaining survival of intestinal epithelial cells during intestinal mucosal barrier dysfunction. A negative regulator of autophagy can lead to intestinal inflammation and tumorigenesis.
Key words: Autophagy, Intestinal mucosal barrier, PI3K/Akt/mTOR signaling pathway, MicroRNA, Wnt/β-catenin signaling pathway
CLC Number:
R574.5
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2017/V37/I3/405