Basic & Clinical Medicine ›› 2016, Vol. 36 ›› Issue (5): 706-710.

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Research progress of CAR-T cells in tumor clinical trials


  • Received:2015-09-21 Revised:2015-12-03 Online:2016-05-05 Published:2016-04-26
  • Contact: Xun LI

Abstract: Currently, chimeric antigen receptor, CAR-related cellular immunotherapy is venerated as the gorgeous star in tumor biotherapy. The CAR-T cell such as which targeted CD19 has obtained the good curative effect in conquering B lymphocyte malignancies. The latest CAT-T related references were collected and summarized to mainly analyse the data of clinical trial, clinical effects and potential adverse reaction treated with CAR-T.

Key words: Chimeric antigen receptor(CAR), T lymphocyte, tumor, clinical trial