Basic & Clinical Medicine ›› 2014, Vol. 34 ›› Issue (11): 1570-1573.

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Betatrophin: a novel factor influences the glucose and lipid metabolism


  • Received:2014-03-13 Revised:2014-04-18 Online:2014-11-05 Published:2014-11-03

Abstract: Betatrophin is a novel factor which regulate the glucose and lipid metabolism. Human betatrophin is located at chromosomal position 19p13.2, and the murine gene is present on chromosome 9. This is a highly conserved gene. Human betatrophin protein shows 73% identity and 82% similarity to the murine protein. It is predominantly expressed in liver and fat, and plays a great role in glucose and lipid metaboslim.

Key words: betatrophin, diabetes mellitus, dyslipidemia

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