Abstract: Objective We try to make a thorough and systemic review on benign recurrent intrahepatic cholestais (BRIC). Methods We made a brief introduction on 1 case of BRIC in Peking Union Medical College Hospital and then browsed qualified BRIC cases on internet databases. Result We found 6 cases in China and 21 cases from abroad. BRIC is characteristic by recurrent cholestasis and pruritus with normal manifestation, biochemical sign and imaging during the interval. The clinical course in most cases is benign, with relatively few cases develop progressive familial intrahepatic cholestasis (PFIC) and have a bad prognosis.

Key words: benign recurrent intrahepatic cholestasis, jaundice, pruritus