Basic & Clinical Medicine ›› 2010, Vol. 30 ›› Issue (9): 988-990.

• 临床园地 • Previous Articles     Next Articles

Benign recurrent intrahepatic cholestasis

Dong-wen CHEN, Dong WU, Xiao-hong SUN, Li-ming ZHU, Gang SUN   

  1. PUMC Hospital, CAMS&PUMC PUMC Hospital, CAMS&PUMC
  • Received:2009-12-30 Revised:2010-01-25 Online:2010-09-05 Published:2010-09-05
  • Contact: Dong WU,

Abstract: Objective We try to make a thorough and systemic review on benign recurrent intrahepatic cholestais (BRIC). Methods We made a brief introduction on 1 case of BRIC in Peking Union Medical College Hospital and then browsed qualified BRIC cases on internet databases. Result We found 6 cases in China and 21 cases from abroad. BRIC is characteristic by recurrent cholestasis and pruritus with normal manifestation, biochemical sign and imaging during the interval. The clinical course in most cases is benign, with relatively few cases develop progressive familial intrahepatic cholestasis (PFIC) and have a bad prognosis.

Key words: benign recurrent intrahepatic cholestasis, jaundice, pruritus