Basic & Clinical Medicine ›› 2010, Vol. 30 ›› Issue (8): 885-888.

• 短篇综述 • Previous Articles     Next Articles

The mechanism of mesenchymal stem cell therapy for diabets

Hong-bin XIE, Hui QI, Fu-rong LI   

  1. Clinical Research Center ,The Second Clinical Medical College Shenzhen People's Hospital,Jinan University
  • Received:2009-09-16 Revised:2009-11-14 Online:2010-08-05 Published:2010-08-05

Abstract: Mesenchymal stem cells (MSCs) after transplantation to diabetic rats reduced blood glucose levels quickly and effectively, reversed the symptoms of high blood sugar in diabetic rats. The mechanism that MSCs treate diabetes may be associated with transdifferentiation, cell fusion,DNA methylation, paracrine mechanism and endogenous pancreatic stem cells.In this paper, we write a review about the current mechanism of mesenchymal stem cell therapy for diabetes

Key words: Mesenchymal stem cell, Islet-like cell, Differentiation mechanism

CLC Number: