Basic & Clinical Medicine ›› 2010, Vol. 30 ›› Issue (6): 582-586.

• 研究论文 • Previous Articles     Next Articles

Relationship between Central and Peripheral Obesity and Ventricular Repolarization Inconsistencies of Adults from Heilongjiang Province

Cheng XU, Xiao-lin YANG, Guang-jin ZHU, Zheng-guo ZHANG   

  1. School of Basic Medicine, PUMC, Institute of Basic Medical Science, CAMS IBMS, CAMS, School of Basic Medicine of PUMC
  • Received:2010-03-19 Revised:2010-03-24 Online:2010-06-05 Published:2010-06-05
  • Contact: Zheng-guo ZHANG

Abstract: Objective Investigate the relationship between central obesity, which is evaluated by waist circumference (WC) and waist-to-hip ratio (WHR), peripheral obesity, which is measured by body mass index (BMI), and ventricular repolarization inconsistencies. Methods Standard 12-lead ECGs of 2045 adults from Heilongjiang Province were measured with Philips Trim II electrocardiograph. QTc were calculated and corrected by Bazett formula. We used the criterion that QTc>440ms was abnormal. Results QTc and abnormal rates increased with age or obesity indices in both male and female. Females' QTc and abnormal rates were significantly higher than the males'. Logistic regression analysis showed that age, gender, heart rate and systolic blood pressure (SBP) had significant effect on QTc abnormal. BMI, WC and WHR also had significant effect on QTc abnormal. WC was the most significant one. Conclusion Obesity is a significant and independent factor to QTc and abnormal rates. Obesity is significantly correlated with ventricular repolarization inconsistencies. Central obesity has more advantages in weighing adults' ventricular repolarization inconsistencies than peripheral obesity.

Key words: ventricular repolarization inconsistencies, QT interval, central obesity, peripheral obesity