Abstract: Objective 　To establish Lung function reference values and prediction equations in children and adolescents of the Han nationality in Heilongjiang province. Methods 　A survey in 588 healthy children and adolescents (292 males , 296 females) aged 10 to 18 years old was carried out in Heilongjiang province in 2008. Eight flow-volume tests parameters [e. g. forced vital capacity (FVC) , forced expiratory volume at one second(FEV1)] were measured. Stepwise multiple regression was carried out to establish prediction equations for the parameters mentioned above. The difference between observed values and the predicted values derived from current authors' and other related prediction equations were compared. Results FVC and FEV1, were found, regardless of sex, to tend to go up with the increase of age( P all <0.001). Beginning from the age of 14, male FVC and FEV1 became significantly higher than those of the female( P < 0. 001), the period of sudden increase of the male FVC and FEV1 taking place during the age of 13-14, while that of the female taking place in the age of 12-13, one age bracket earlier than the male. All lung volumes and flow rates, were found, regardless of sex, to tend to go up with the increase of age, height and weight(P all< 0.001). The correlation among lung function parameters was higher in height than weight and age. The regression equations of lung function were established. By comparison with the equations derived from our study and other authors' study, it was found that the difference between measured data and predicted values from other authors were higher than those from ours. Conclusion　Reference values and prediction equations for forced expiratory lung function applicable for children and adolescents of the Han nationality in Heilongjiang province were established.

Key words: ventilatory function, children, adolescents, the Han nationality, Reference values, prediction equation