Abstract: The wnt/β-catenin signal transduction pathway is an access regulating cell proliferation, movement, differentiation and plays crucial roles in embryo development. The researchers have found that Wnt pathway is an important regulation factor in the early stimulation of the cardiogenesis and contacts closely the several key events during cardiac morphogenesis. The article reviews the recent studies about the relation between cardiac development and Wnt pathway in early embryo.

Key words: wnt/β-catenin signal transduction, early of embryo, heart