Basic & Clinical Medicine ›› 2009, Vol. 29 ›› Issue (9): 984-986.

• 临床园地 • Previous Articles     Next Articles

Diagnosis and treatment of renal oncocytoma and chromophobe cell renal carcinoma

Hai-dong WANG, Ping ZHANG, Li-bo MAN, Yu-hai ZHANG   

  1. Beijing Jishuitan Hospital
  • Received:2008-07-21 Revised:2009-01-07 Online:2009-09-20 Published:2009-09-20
  • Contact: Hai-dong WANG,

Abstract: Objective To evaluate the clinical characteristic, diagnosis and treatment procedures for renal oncocytoma and chromophobe cell renal carcinoma. Methods 8 cases of renal oncocytoma and 5 cases of chromophobe cell renal carcinoma were analysed. The average of oncocytoma was 58.8 years old(23~74),and mean tumor size was 5.1 cm(range, 3~7cm); The mean age of chromophobe cell renal carcinoma was 54.5 years old(35~72),and mean tumor size was 5.8 cm(range, 3~8cm). Doppler ultrasonography and CT scan were performed in all patients. All cases accepted surgical operation and were confirmed by pathology. Results Renal oncocytoma was characterized by homogeneous round cell containing aboundant axyphil pellets. color Doppler ultrasonography mainly show isoechoic or hypoechoic masses .CT scan revealed that the tumors were homogeneous solid masses, and most of them were visualized as homogeneous enhancement.All the patients were followed up for 10 to 53 months,and no recurrence or metastasis noted. Chromophobe cell carcinoma composed of two cell types, typical and eosinophilic type, These cells were characterized by fine reticular cytoplasm and clear cell border. Color Doppler ultrasonography show mainly hyperechoic masses, CT scan revealed most of the tumors were heterogeneous enhancement.All the patients were followed up for 12 to 49 months,and 1 case died from metastasis after 1 year. Conclusion Renal oncocytoma and chromophobe cell renal carcinoma can be differentiated by clinical characteristic,ultrasonic, and CT scan. The final diagnosis depends on the pathology. Partial nephrectomy is good for renal oncocytoma, while radical nephrectomy is the first choice for chromophobe cell renal carcinoma.

Key words: renal oncocytoma, chromophobe cell renal carcinoma, diagnosis, treatment