Abstract: The main objective of today's graduate education reform is to improve the quality of graduate students. Curriculum development, as an essential part of graduate education, is pivotal to this goal. While classroom teaching innovation is placed in the front of curriculum development, it has become an important issue for graduate education study to practice an alternative ability centered way other than the current knowledge centered classroom teaching. They offered the course called "literature presentation and discussion" to the class 2006 graduate students at Chinese Academy of Medical Sciences. This article outlined and discussed the purpose，practice of this course，feedbacks from students and problems and solutions.

Key words: graduate education, classroom teaching innovation, literature presentation and discussion.