基础医学与临床 ›› 2021, Vol. 41 ›› Issue (4): 593-597.

• 短篇综述 • 上一篇    下一篇

肠道微生物失衡在慢性便秘中作用的研究进展

杨晶晶, 陈嘉屿*   

  1. 中国人民解放军联勤保障部队第九四〇医院 消化内科, 甘肃 兰州 730000
  • 收稿日期:2020-08-10 修回日期:2020-12-16 出版日期:2021-04-05 发布日期:2021-04-05
  • 通讯作者: *chenjiayu65@163.com
  • 基金资助:
    军委后勤保障部卫生局保健专项(17BJZ25)

Research progress on the role of intestinal microbial imbalance in chronic constipation

YANG Jing-jing, CHEN Jia-yu*   

  1. Department of Gastroenterology, the 940th Hospital of the Joint Logistics Support Force of People's Liberation Army of China, Lanzhou 730000, China
  • Received:2020-08-10 Revised:2020-12-16 Online:2021-04-05 Published:2021-04-05
  • Contact: *chenjiayu65@163.com

摘要: 慢性便秘为功能性便秘的原型,其患病率随年龄的增加而逐渐升高。肠道微生物参与了慢性便秘的发生发展、病理生理等过程,其可调节胃肠道的运动功能,肠道微生物的动态平衡遭到破坏可导致慢性便秘的发生。

关键词: 慢性便秘, 肠道微生物, 机制

Abstract: Chronic constipation is the prototype of functional constipation, and its morbidity increases gradually with aging. Intestinal microorganisms are involved in the occurrence, development, pathophysiology and other processes of chronic constipation. They can regulate the motor function of the gastrointestinal tract, and the destruction of the dynamic balance of intestinal microorganisms can lead to the occurrence of chronic constipation.

Key words: chronic constipation, intestinal microorganism, mechanism

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