基础医学与临床 ›› 2021, Vol. 41 ›› Issue (2): 282-286.

• 短篇综述 • 上一篇    下一篇

Salusin-β在心血管疾病中作用的研究进展

时英1,2, 郭永芳4, 邓玉婷2, 戴红艳2, 管军3*   

  1. 1.大连医科大学,辽宁 大连 116044; 青岛市市立医院 2.保健四科; 3.心内科,山东 青岛 266000;
    4.青岛大学附属医院 心内科, 山东 青岛 266000
  • 收稿日期:2020-08-26 修回日期:2020-11-04 出版日期:2021-02-05 发布日期:2021-01-19
  • 通讯作者: *guanjun@medmail.com.cn
  • 基金资助:
    青岛市医疗卫生优秀学科带头人计划 (青卫科教字[2019] 9号)

Research progress on the role of Salusin-β in cardiovascular diseases

SHI Ying1,2, GUO Yong-fang4, DENG Yu-ting2, DAI Hong-yan2, GUAN Jun3*   

  1. 1. Dalian Medical University, Dalian 116044; 2. Department of Healthcare Ⅳ; 3. Department of Cardiology,Qingdao Municipal Hospital, Qingdao 266000;
    4. Department of Cardiology,the Affiliated Hospital of Qingdao University,Qingdao 266000,China
  • Received:2020-08-26 Revised:2020-11-04 Online:2021-02-05 Published:2021-01-19
  • Contact: *guanjun@medmail.com.cn

摘要: Salusin-β是一种生物活性肽,其在促进动脉粥样硬化、升高血压、促进心肌细胞肥大、参与血管平滑肌细胞增殖及抗炎性反应等方面起着重要的作用。Salusin-β对心血管疾病的预后有一定的预测价值,有望为心血管疾病的治疗提供新的靶点和方向。

关键词: salusin-β, 生物活性肽, 心血管疾病, 治疗

Abstract: Salusin-β is a biologically active peptide, which plays an important role in promoting atherosclerosis, raising blood pressure, promoting cardiomyocyte hypertrophy, participating in vascular smooth muscle cell proliferation and anti-inflammatory response. Salusin-β has certain predictive value for the prognosis of cardiovascular diseases, it is expected to find targets and thus support the treatment of cardiovascular diseases.

Key words: salusin-β, bioactive peptide, cardiovascular diseases, therapy

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