基础医学与临床 ›› 2019, Vol. 39 ›› Issue (1): 110-114.
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欧洁,吴红艳
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摘要: 调节性B细胞是新近发现的B细胞子集,其在抑制肿瘤免疫和促进肿瘤细胞的增殖和转移中起重要作用。Bregs可通过分泌IL-10、IL-35和TGF-β等细胞因子抑制多种细胞亚型,从而抑制抗肿瘤免疫应答。
关键词: 调节性B细胞, 肿瘤, 细胞因子
Abstract: Regulatory B cells are a newly designated subset of B cells that have shown to play a significant role in inhibiting tumor immunity and promoting the proliferation and metastasis of tumor cells. Bregs can suppress diverse cell subtypes through the secretion of cytokines, such as IL-10, IL-35 and TGF-β, thus attenuating anti-tumor immune responses.
Key words: regulatory B cells, tumor, cytokines
中图分类号:
R730.3
欧洁 吴红艳. 调节性B细胞对肿瘤发展促进作用的研究进展[J]. 基础医学与临床, 2019, 39(1): 110-114.
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