基础医学与临床 ›› 2016, Vol. 36 ›› Issue (3): 406-410.

• 短篇综述 • 上一篇    下一篇

脑电图技术在帕金森病临床研究中的应用

王培培1,王静1,陈昭燃2,李俊发1   

  1. 1. 首都医科大学
    2. 首都医科大学神经生物学系
  • 收稿日期:2015-07-16 修回日期:2015-11-04 出版日期:2016-03-05 发布日期:2016-02-22
  • 通讯作者: 陈昭燃 E-mail:18510437966@163.com
  • 基金资助:
    科研基地-科技创新平台-神经科学基础临床研究平台建设

The clinical application of EEG in Parkinson's disease research

  • Received:2015-07-16 Revised:2015-11-04 Online:2016-03-05 Published:2016-02-22
  • Supported by:
    Scientific Research Base - Science and Technology Innovation Platform - the Platform Construction of Neuroscience Based Clinical Research

摘要: 帕金森病(PD)是中老年期高发神经退行性疾病之一,其特点是患者出现明显症状时不可逆转的神经变性已发生,治疗与预后均不理想。脑电图(EEG)是神经科学研究的重要内容与手段,能够以高时间分辨率连续记录全脑电活动,并被广泛应用于PD研究中。本文回顾EEG在PD临床研究中的应用,从非运动症状、运动症状研究和疗效评估三方面展开。最后论述其临床应用优势,并讨论EEG的局限性及其应用展望。

关键词: 帕金森病, 脑电图, 临床应用, 优势, 局限性

Abstract: Parkinson's disease (PD) is a common neurodegenerative disease in middle-aged and elderly population. PD patients with observable symptoms suffer from irreversible degeneration of neural system, but the treatment and prognosis are challenging. Electroencephalography (EEG) is an important approach in neuroscience research, which could record electrical signals from the entire brain with high temporal resolution, and it is widely applied to clinical PD research. This review focuses on EEG investigations on non-motor symptoms, motor symptoms, and treatment efficacy of PD. The advantages and limitations of EEG technique in clinical applications are also discussed.

Key words: Parkinson's disease, Electroencephalography, clinical application, advantage, limitation

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