基础医学与临床 ›› 2013, Vol. 33 ›› Issue (5): 597-600.

• 研究论文 • 上一篇    下一篇

原发性气管肿瘤的外科治疗

王珍1,王剑1,梁乃新2,祝小莉3,李五一1   

  1. 1. 中国医学科学院北京协和医学院北京协和医院
    2. 北京协和医院
    3. 中国医学科学院 北京协和医学院 北京协和医院
  • 收稿日期:2013-01-07 修回日期:2013-03-25 出版日期:2013-05-05 发布日期:2013-05-29
  • 通讯作者: 李五一 E-mail:liwuyi@sina.com

Surgical Treatment of Primary Tracheal Tumors

  • Received:2013-01-07 Revised:2013-03-25 Online:2013-05-05 Published:2013-05-29

摘要: 目的 总结原发性气管肿瘤的临床特点和外科治疗策略。 方法 回顾性分析北京协和医院自1991年12月~2012年2月收治的30例原发性气管肿瘤的临床资料,其中恶性肿瘤占28/30,腺样囊性癌占18/30,鳞癌占5/30,其它肿瘤占7/30。对其中资随访资料完整的28例进行统计学分析Kaplan-Meier法计算生存曲线,对可能的预后危险因素进行Log-Rank检验分析。 结果 原发性气管恶性肿瘤的5年和10年生存率分别为56.0%和18.7%。腺样囊性癌患者的显微镜下无残留切除率显著低于其他恶性肿瘤(Χ2=7.667,p<0.05)。手术切缘阳性与否对于生存的影响组间无差异。术后放疗与否对于生存的影响组间无差异。结论 原发性气管肿瘤起病隐匿,临床少见,手术切除是首选的治疗方法。

关键词: 气管肿瘤, 癌, 生存率, 预后

Abstract: Objective To investigate the clinical characteristics and treatment of primary tracheal tumors. Methods The clinical data of 30 cases with primary tracheal tumors admitted in Peking Union Medical College Hospital from December 1991 to February 2012 were analyzed retrospectively. 28/30 of cases were malignant, 18/30 of cases were adenoid cystic carcinoma (ACC) , 5/30 were squamous cell carcinoma and 7/30 were other tumors. The survival rates were analyzed by Kaplan-Meier. The possible prognostic risk factors were tested by Log-Rank test. Results The 5-year and 10-year survival rates were 56.0% and 18.7%. The R0 resection rate of ACC group was significantly lower than the non-ACC group(Χ2=7.667,p<0.011). Positive margin showed no significant relationship with survival rate. Post-operation radiation therapy showed no significant relationship with survival rate. Conclusion Primary tracheal tumors are difficult to diagnose at the onset of the disease and the incidence of the disease is low. Surgical treatment is the first choice.

Key words: tracheal neoplasm, carcinoma, survival rate, prognosis

中图分类号: