基础医学与临床 ›› 2012, Vol. 32 ›› Issue (8): 960-963.

• 短篇综述 • 上一篇    下一篇

肿瘤标志物在乳腺癌诊断及预后中的应用

董晓民1,钟理1,樊江平1,陈保平2,臧爱民3   

  1. 1. 河北大学生命科学学院生物芯片研究室
    2. 河北大学附属医院肿瘤外科
    3. 河北大学附属医院
  • 收稿日期:2011-12-26 修回日期:2012-03-01 出版日期:2012-08-05 发布日期:2012-07-17
  • 通讯作者: 钟理 E-mail:lee_z@yahoo.com
  • 基金资助:
    骨髓间充质干细胞瘤化中STAT3信号通路过度激活的作用机制与规避研究

Application of tumor markers in breast cancer diagnosis and prognosis

  • Received:2011-12-26 Revised:2012-03-01 Online:2012-08-05 Published:2012-07-17

摘要: 肿瘤标志物已广泛应用于乳腺癌的诊断及预后。本文总结了CA15-3、HER2、ER及PR等经典乳腺癌标志物的临床应用现状,及新兴乳腺癌生物标志的临床价值。多标志物的联合检测较单一标志物有更高的灵敏度及特异性,将成为今后乳腺癌标志物的临床应用趋势。

关键词: 肿瘤标志物, 乳腺癌, 诊断, 预后

Abstract: Tumor markers have been widely used in diagnosis and prognosis of breast cancer. This article reviews the clinical applications of classic breast cancer biomarkers, such as CA15-3, HER2, ER and PR, and the clinical values of emerging biomarkers of breast cancer. Combined detection with multi-biomarkers has higher sensitivity and specificity than detection with single tumor marker, and will become a trend how breast cancer biomarkers are used in clinical treatment.

Key words: tumor markers, breast cancer, diagnosis, prognosis

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