基础医学与临床 ›› 2012, Vol. 32 ›› Issue (8): 960-963.
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董晓民1,钟理1,樊江平1,陈保平2,臧爱民3
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摘要: 肿瘤标志物已广泛应用于乳腺癌的诊断及预后。本文总结了CA15-3、HER2、ER及PR等经典乳腺癌标志物的临床应用现状,及新兴乳腺癌生物标志的临床价值。多标志物的联合检测较单一标志物有更高的灵敏度及特异性,将成为今后乳腺癌标志物的临床应用趋势。
关键词: 肿瘤标志物, 乳腺癌, 诊断, 预后
Abstract: Tumor markers have been widely used in diagnosis and prognosis of breast cancer. This article reviews the clinical applications of classic breast cancer biomarkers, such as CA15-3, HER2, ER and PR, and the clinical values of emerging biomarkers of breast cancer. Combined detection with multi-biomarkers has higher sensitivity and specificity than detection with single tumor marker, and will become a trend how breast cancer biomarkers are used in clinical treatment.
Key words: tumor markers, breast cancer, diagnosis, prognosis
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R737.9
董晓民 钟理 樊江平 陈保平 臧爱民. 肿瘤标志物在乳腺癌诊断及预后中的应用[J]. 基础医学与临床, 2012, 32(8): 960-963.
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