基础医学与临床 ›› 2008, Vol. 28 ›› Issue (12): 1300-1302.

• 研究论文 • 上一篇    下一篇

7925例遗传咨询者细胞遗传学分析

景晓红 李俊华 秦翠云 剡宏民 强荣 郑军   

  1. 西安医学院细胞生物与遗传教研室
  • 收稿日期:2008-03-14 修回日期:2008-08-04 出版日期:2008-12-25 发布日期:2008-12-25
  • 通讯作者: 景晓红

7,925 cases of genetic counseling Cytogenetic analysis

Xiao-hong JING, Jun-hua LI, Cui-yun QIN, Hong-min YAN, Rong QIANG, Jun ZHENG   

  1. Department of cell biology and genetic ,Xi'an Medical College
  • Received:2008-03-14 Revised:2008-08-04 Online:2008-12-25 Published:2008-12-25
  • Contact: Xiao-hong JING,

摘要: 目的 通过7925例遗传咨询者的染色体检查和分析,说明染色体异常对流产、智力低下、原发闭经等的影响。方法 对待检者进行外周血培养、染色体G显带分析。 结果 共检出染色体异常核型221例,异常率2.78%。其中常染色体异常172例,占2.17%;性染色体异常49例,占0.62%;经有关专家鉴定有13种核型为世界首报。 结论 染色体异常是引起自然流产、畸胎、智力低下、女性原发闭经的重要原因。

关键词: 遗传咨询, 遗传

Abstract: Objective 7,925 cases of genetic counseling through the examination and analysis of chromosomes that chromosomal abnormalities on abortion, mental retardation, primary amenorrhea impact. Methods Deal with the seizure of a blood culture, the G-band-ing chromosome analysis. Results Chromosomal abnormalities were detected 221 cases of nuclear, abnormal rate of 2.78 percent.Of which 172 cases often chromosomal abnormalities, or 2.17 percent, 49 cases of chromosome abnormalities, or 0.62 percent, as experts have identified 13 species of the world's first nuclear reported. Conclusions Chromosomal abnor-malities cause spontaneous abortion,teratogenic,mental retardation,female primary amenorrhea an important reason.