Page 19 - Demo

%u4e0e%u963f%u7247%u6837%u76f8%u4f3c%u7684%u4f5c%u7528%u6548%u679c%uff3b%uff16%uff18%uff3d%u3002%u56e0%u6b64 %uff2e%uff30%uff26%uff26%u5bf9%u4e8e%u589e%u5f3a%u963f%u7247%u7c7b%u836f%u7269%u7684%u9547%u75db%u6548%u679c%u548c%u964d%u4f4e%u5176%u6f5c%u5728%u526f%u4f5c%u7528%u5177%u6709%u5173%u952e%u6027%u5f71%u54cd%u3002%uff37%uff41%uff4e%uff47%u7b49%uff3b%uff16%uff19%ue011%uff17%uff11%uff3d%u901a%u8fc7%u591a%u80bd%u5206%u5b50%u5d4c%u5408%u7b56%u7565%u8bbe%u8ba1%u4e86%u4e00%u7cfb%u5217%u5177%u6709 %uff2d%uff2f%uff32%uff0f%uff2e%uff30%uff26%uff26%uff32%u53cc%u9776%u70b9%u6d3b%u6027%u7684%u5316%u5408%u7269%uff0c%u5305%u62ec %uff25%uff2e%ue011%uff19%uff08%uff12%uff11%uff09%u3001%uff22%uff2e%ue011%uff19%uff08%uff12%uff12%uff09%u548c %uff24%uff2e%ue011%uff19%uff08%uff12%uff13%uff09%u7b49%uff08%u56fe %uff19%uff09%u3002%u5176%u4e2d %uff24%uff2e%ue011%uff19%u53ef%u4ee5%u540c%u65f6%u6fc0%u6d3b%uff2d%uff2f%uff32%u548c %uff2e%uff30%uff26%uff26%uff32%uff0c%u5bf9%u6025%u6027%u3001%u708e%u6027%u548c%u795e%u7ecf%u6027%u75bc%u75db%u5177%u6709%u5f3a%u6548%u9547%u75db%u4f5c%u7528%uff0c%uff25%uff24%uff15%uff10%u503c%u4ecb%u4e8e%uff10%ue010%uff16%uff16%uff5e%uff15%uff15%ue010%uff10%uff14%uff50%uff4d%uff4f%uff4c%u95f4%u3002%u6b64%u5916%uff0c%uff22%uff41%uff4c%uff4c%uff45%uff54%u7b49%uff3b%uff17%uff12%uff3d%u7814%u7a76%u53d1%u73b0%u4e86%u4e00%u7cfb%u5217%u963f%u7247%uff0f%uff2e%uff30%uff26%uff26%uff32%u7684%u591a%u9776%u70b9%u5316%u5408%u7269%uff0c%u5176%u4e2d %uff2b%uff27%ue011%uff26%uff26%uff10%uff19%uff08%uff12%uff14%uff0c%u56fe %uff19%uff09%u4e3a%u53cc%u529f%u80fd %uff2d%uff2f%uff32%u6fc0%u52a8%u5242 %uff0f%uff2e%uff30%uff26%uff26%uff32%u62ee%u6297%u5242%u62df%u80bd%u7c7b%u836f%u7269%uff0c%u5b83%u80fd%u591f%u6709%u6548%u7f13%u89e3%u4f24%u5bb3%u6027%u75bc%u75db%u3001%u5185%u810f%u75bc%u75db%u4ee5%u53ca%u6162%u6027%u708e%u75c7%u6027 %u75bc %u75db %u7b49 %u591a %u79cd %u75bc %u75db %u72b6 %u51b5%uff0c%u5e76 %u4e14 %u672a %u51fa %u73b0 %u9547 %u75db %u8010 %u53d7%u73b0%u8c61%uff3b%uff17%uff13%uff3d%u3002%u73b0%u6709%u9488%u5bf9 %uff2d%uff2f%uff32%uff0f%uff2e%uff30%uff26%uff26%uff32%u53cc%u9776%u70b9%u836f%u7269%u7684%u7814%u7a76%u8868%u660e%uff0c%u8be5%u7c7b%u5316%u5408%u7269%u5177%u6709%u5f3a%u9547%u75db%u4f5c%u7528%u548c%u4f4e%u526f%u4f5c%u7528%u7279%u70b9%uff0c%u4f46%u8981%u5b8c%u5168%u7406%u89e3%u8fd9%u4e24%u79cd%u53d7%u4f53%u7cfb%u7edf%u5982%u4f55%u76f8%u4e92%u4f5c%u7528%u4ee5%u51cf%u5c11%u963f%u7247%u7c7b%u836f%u7269%u7684%u526f%u4f5c%u7528%uff0c%u8fd8%u9700%u8981%u8fdb%u4e00%u6b65%u7684%u7814%u7a76%u3002NO HN NH OO HNONHN NHHNOOOOOOONHHNOH22 (BN-9)HONHNHNNO OHNHNNHOOONHO23 (DN-9) 24 (KGFF09)OHNHN NHOOO HN NHN NH OOOOOO HNHN NHOO21(EN-9)HONH2HN HNOONO HNONO HNONHOO HNHN NHONH2NH2NH2NH2NH2NH2NH2NH2NH2NH2NH2NH2NH2 NH2N2H N2HOEC50 %u00b5 = 38.6 nmol%u00b7L-1EC50 NPFF1R = 973.4 nmol%u00b7L-1EC50 NPFF2R = 310.8 nmol%u00b7L-1Ki %u00b5 = 2.43 nmol%u00b7L-1Ki NPFF1 R = 83 nmol%u00b7L-1Ki NPFF2R = 3.2 nmol%u00b7L-1EC50%u00b5 = 4.44 %u00b5mol%u00b7L-1EC50 NPFF1R = 598.6 nmol%u00b7L-1EC50 NPFF2 R =25.3 nmol%u00b7L-1EC50 %u00b5 = 308.2 nmol%u00b7L-1EC50 NPFF1R = 591.0 nmol%u00b7L-1EC50 NPFF2R = 184.6 nmol%u00b7L-1%uff2b%uff49%uff2e%uff30%uff26%uff26%uff11%uff32%uff0d%u5316%u5408%u7269%u5bf9%u795e%u7ecf%u80bd %uff26%uff26%uff11%u53d7%u4f53%u7684%u7ed3%u5408%u4eb2%u548c%u529b%uff1b%uff2b%uff49%uff2e%uff30%uff26%uff26%uff12%uff32%uff0d%u5316%u5408%u7269%u5bf9%u795e%u7ecf%u80bd %uff26%uff26%uff12%u53d7%u4f53%u7684%u7ed3%u5408%u4eb2%u548c%u529b%uff1b%uff25%uff23%uff15%uff10%uff2e%uff30%uff26%uff26%uff11%uff32%uff0d%u5316%u5408%u7269%u4e0e%u795e%u7ecf%u80bd %uff26%uff26%uff11%u53d7%u4f53%u7ed3%u5408%u65f6%u4ea7%u751f%uff15%uff10%uff05%u6700%u5927%u751f%u7269%u6548%u5e94%u7684%u6d53%u5ea6%uff1b%uff25%uff23%uff15%uff10%uff2e%uff30%uff26%uff26%uff12%uff32%uff0d%u5316%u5408%u7269%u4e0e%u795e%u7ecf%u80bd %uff26%uff26%uff12%u53d7%u4f53%u7ed3%u5408%u65f6%u4ea7%u751f %uff15%uff10%uff05%u6700%u5927%u751f%u7269%u6548%u5e94%u7684%u6d53%u5ea6%u3002%u56fe %uff19 %u03bc%u963f%u7247%u53d7%u4f53%uff0f%u795e%u7ecf%u80bd %uff26%uff26%u53d7%u4f53%uff08%uff2d%uff2f%uff32%uff0f%uff2e%uff30%uff26%uff26%uff32%uff09%u53cc%u9776%u70b9%u6d3b%u6027%u914d%u4f53%uff3b%uff16%uff17%ue011%uff17%uff12%uff3d%uff12%ue010%uff18 %uff2d%uff2f%uff32%uff0f%uff24%uff13%uff32%u53cc%u9776%u70b9%u5316%u5408%u7269%u591a%u5df4%u80fa%uff08%uff44%uff4f%uff50%uff41%uff4d%uff49%uff4e%uff45%uff0c%uff24%uff21%uff09%u662f%u4e2d%u67a2%u795e%u7ecf%u548c%u5468%u56f4%u795e%u7ecf%u7cfb%u7edf%u7684%u4e00%u79cd%u5173%u952e%u795e%u7ecf%u9012%u8d28%uff0c%u591a%u5df4%u80fa%u53d7%u4f53%u5206%u4e3a %uff24%uff11%u6837%u548c %uff24%uff12%u6837%u4e24%u7c7b%uff0c%uff24%uff13%uff32%u5c5e%u4e8e %uff24%uff12%u6837%u53d7%u4f53%u5bb6%u65cf%uff0c%u540c%u6837%u5c5e%u4e8e %uff27%u86cb%u767d%u5076%u8054%u53d7%u4f53%u3002%u7814%u7a76%u53d1%u73b0%uff0c%uff24%uff13%uff32%u662f%u963f%u7247%u7c7b%u836f%u7269%u4f7f%u7528%u969c%u788d%u7684%u6f5c%u5728%u6cbb%u7597%u9776%u70b9%uff3b%uff17%uff14%uff3d%uff0c%u963b%u65ad%uff24%uff13%uff32%u53ef%u51cf%u8f7b%u963f%u7247%u7c7b%u836f%u7269%u5f15%u8d77%u7684%u6210%u763e%u884c%u4e3a%uff3b%uff17%uff15%uff3d%u3002%u56e0%u6b64%uff0c%u5b66%u8005%u5bf9%uff2d%uff2f%uff32%uff0f%uff24%uff13%uff32%u53cc%u9776%u70b9%u5316%u5408%u7269%u5c55%u5f00%u7814%u7a76%uff0c%u4ee5%u671f%u671b%u7ed3%u5408%u4e24%u8005%u7684%u4f18%u52bf%uff0c%u63d0%u4f9b%u66f4%u6709%u6548%u7684%u6cbb%u7597%u9009%u62e9%u3002%uff12%uff10%uff12%uff11%u5e74 %uff22%uff4f%uff4e%uff49%uff46%uff41%uff5a%uff49%u7b49%uff3b%uff17%uff16%uff3d%u5229%u7528%u8ba1%u7b97%u8f85%u52a9%u836f%u7269%u8bbe%u8ba1%u7b56%u7565%uff0c%u57fa%u4e8e%u4e0d%u540c%u7684%u5316%u5b66%u9aa8%u67b6%u548c%u4f53%u5916%u7ed3%u5408%u5b9e%u9a8c%uff0c%u7b5b%u9009%u51fa%u4e86%u5177%u6709%u9ad8%u7ed3%u5408%u4eb2%u548c%u529b%u7684 %uff2d%uff2f%uff32%uff0f%uff24%uff13%uff32%u53cc%u9776%u70b9%u5316%u5408%u7269 %uff12%uff15%u7b49%uff08%u56fe %uff11%uff10%uff09%uff0c%u5728%u4fdd%u6301%u9547%u75db%u7597%u6548%u7684%u540c%u65f6%u53ef%u4ee5%u51cf%u5c11%u963f%u7247%u7c7b%u836f%u7269%u6ee5%u7528%u3002%uff12%uff10%uff12%uff13%u5e74%u8be5%u8bfe%u9898%u7ec4%u9488%u5bf9 %uff2d%uff2f%uff32%uff0f%uff24%uff13%uff32%u53cc%u9776%u70b9%u7ee7%u7eed%u5c55%u5f00%u7814%u7a76%uff0c%u53d1%u73b0%u53cd%u5f0f%ue011%uff08%uff12%uff33%uff0c%uff14%uff32%uff09%ue011%u5421%u54af%u70f7%u548c%u53cd%u5f0f%u82ef%u57fa%u73af%u4e19%u80fa%u662f%u5f71%u54cd%u591a%u5df4%u80fa%u80fd%u6d3b%u6027%u7684%u5173%u952e%u7ed3%u6784%u7247%u6bb5%uff0c%u5e76%u901a%u8fc7%u4e0e%u963f%u7247%u7c7b%u836f%u7269%u9aa8%u67b6%u8fdb%u884c%u878d%u5408%uff0c%u5f97%u5230%u4e00%u7cfb%u5217%u5177%u6709%u6f5c%u5728%u6cbb%u7597%u4ef7%u503c%u7684%u65b0%u578b%u5316%u5408%u7269%uff0c%u5176%u4e2d%u5316%u5408%u7269 %uff12%uff16%u3001%uff12%uff17%u901a%u8fc7 %uff2d%uff2f%uff32%u90e8%u5206%u6fc0%u52a8%u4f5c%u7528%u4ea7%u751f%u9547%u75db%u4f5c%u7528%uff0c%u5e76%u901a%u8fc7 %uff24%uff13%uff32%u62ee%u6297%u4f5c%u7528%u51cf%u5c11%u963f%u7247%u6ee5%u7528%uff3b%uff17%uff17%uff3d%u3002%u56e0%u6b64%uff0c%u8bbe%u8ba1%u5177%u6709%uff2d%uff2f%uff32%uff0f%uff24%uff13%uff32%u53cc%u9776%u70b9%u6d3b%u6027%u7684%u5316%u5408%u7269%uff0c%u4e3a%u964d%u4f4e%u6210%u763e%u6027%u7684%u4f53%u5185%u9547%u75db%u63d0%u4f9b%u4e86 %u53ef %u80fd%uff0c%u5e76 %u4e3a %u5f00 %u53d1 %u66f4 %u5b89 %u5168 %u7684 %u9547 %u75db %u836f %u63d0 %u4f9b %u4e86 %u65b0 %u7684%u65b9%u5411%u3002NNO NClClNONHO HNO N NCl Cl NONNClCl25Ki %u00b5 = 0.832 nmol%u00b7L-1Ki D3R =171 nmol%u00b7L-1Ki %u00b5 = 564 nmol%u00b7L-1Ki D3R= 7.26 nmol%u00b7L-1Ki %u00b5 = 691 nmol%u00b7L-1Ki D3R = 46.5 nmol%u00b7L-126 27%uff2b%uff49%uff24%uff13%uff32%uff0d%u5316%u5408%u7269%u5bf9%u591a%u5df4%u80fa %uff24%uff13%u53d7%u4f53%u7684%u7ed3%u5408%u4eb2%u548c%u529b%u3002%u56fe %uff11%uff10 %u03bc%u963f%u7247%u53d7%u4f53%uff0f%u591a%u5df4%u80fa %uff24%uff13%u53d7%u4f53%uff08%uff2d%uff2f%uff32%uff0f%uff24%uff13%uff32%uff09%u53cc%u9776%u70b9%u6d3b%u6027%u914d%u4f53%u00b7%uff12%uff11%uff11%uff12%u00b7 %uff23%uff48%uff49%uff4e%uff30%uff48%uff41%uff52%uff4d%uff2a%uff0c%uff12%uff10%uff12%uff14%uff2e%uff4f%uff56%uff45%uff4d%uff42%uff45%uff52%uff0c%uff36%uff4f%uff4c%ue010%uff15%uff19%uff2e%uff4f%ue010%uff12%uff12 %u4e2d%u56fd%u836f%u5b66%u6742%u5fd7 %uff12%uff10%uff12%uff14%u5e74 %uff11%uff11%u6708%u7b2c %uff15%uff19%u5377%u7b2c %uff12%uff12%u671f