Abstract: Objective To investigate whether the cardiovascular events and prognosis on non-coronary artery disease and coronary artery disease in 1 month and 6 months could be predicted by baseline levels of C-reactive protein (CRP). Methods Preprocedural serum levels of CRP were measured in 327 patients perpormed with CAG or PCI . the patients were divided into two groups: CRP<0.3mg/dl and CRP≥0.3mg/dl. The cardiovascular events and stent resternosis, re-PCI, CABG, tachycardia arrhythmia were carefully observed and recorded intraprocedural and in 1month and 6 month after the procedures. Results The baseline levels of CRP were significantly higher in the patients with acute coronary syndrome than those with stable angina pectoris and non- coronary artery disease (5.15 ± 0.40 vs 0.27±0.05, 0.26±0.35, P＜0.01). The frequency of cardiovascular events was significantly higher in acute coronary syndrome and high baseline levels of CRP than those with stable angina pectoris and normal baseline levels of CRP in 1 month (4.86% vs 2.44%, P＜0.05; 16.36% vs 3.70%, P<0.01), The cardio vascular events and those in in-stentresternosis,re-PCI,CABG, tachycardia arrhythmia were significantly high in the acute syndrome than those with normal baseline levels of CRP and stable angina pectoris in 6 months too（12.50% vs 6.10%, P<0.05; 26.06% vs 13.58%, P<0.01）.Conclusion Preprocedural CRP level may be a predictor in 1 month and 6 months outcome of patients undergoing CAD after PCI or non-CAD. It indicated that the complications and clinical resternosis in 6 months were markedly influenced by the preprocedual degree of inflammatory cell activation .