Research progress on regulatory mechanisms of circular RNA nuclear receptor interacting protein 1 in tumor occurrence and development

doi:10.16352/j.issn.1001-6325.2023.05.0827

Abstract

Abstract: Circular RNA (circRNA) is a class of single-stranded covalently closed non-coding RNA molecules widely expressed in eukaryotic cells. Recent studies have found that circRNA has been involved in modulating biological processes such as cell proliferation, differentiation, and apoptosis so it is the key regulator of tumor occurrence and development. Circular RNA nuclear receptor interacting protein 1(circ_NRIP1), as a circular RNA, is abnormally expressed in various human cancers and potentially regulates malignant biological behaviors such as tumor proliferation, invasion and migration. Elucidating the regulatory mechanisms of circ_NRIP1 in tumor occurrence and development may provide a new strategy for tumor diagnosis and treatment.

Key words: circular RNA, circular RNA nuclear receptor interacting protein 1(circ_NRIP1), tumor occurrence and development, regulatory mechanism

CLC Number:

R730

GAO Xin, YU Yongbo, WANG Haicun, JIANG Xingming, WANG Zhidong. Research progress on regulatory mechanisms of circular RNA nuclear receptor interacting protein 1 in tumor occurrence and development[J]. Basic & Clinical Medicine, 2023, 43(5): 827-832.

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