Basic & Clinical Medicine ›› 2021, Vol. 41 ›› Issue (6): 895-898.

• Mini Reviews • Previous Articles     Next Articles

Progress in the diagnosis and treatment of cognitive frailty

ZHAO Rui-xue1, MA Ya-jun1, LIU Hui1, LI Xiao-dong1, WANG Xiao-feng2, JIANG Xiao-yan3, LI Shu-juan1*   

  1. 1. Department of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020;
    2. Ministry of Education Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200433;
    3. Department of Pathology and Pathophysiology, Tongji University School of Medicine, Shanghai 200092,China
  • Received:2020-06-01 Revised:2020-08-29 Online:2021-06-05 Published:2021-05-31
  • Contact: *2431965@qq.com

Abstract: Cognitive frailty, which increases the risk of dementia, is a geriatric syndrome characterized by both physical frailty and cognitive impairment. It is associated with adverse health events such as functional disability, hospitalization, falls, all-cause mortality and the incidence of dementia, vascular dementia, neurocognitive disorders, with potential reversibility. A clear and unified operational definition of cognitive frailty in the future is of great significance for early recognition and intervention of cognitive frailty and secondary prevention of early or asymptomatic dementia.

Key words: cognitive frailty, physical frailty, cognitive dysfunction, frailty models, adverse health events

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