Regulatory effects and mechanisms of HOTAIRM1 in malignant tumors

Abstract

Abstract: HOTAIRM1, a newly found long non-coding RNA (lncRNA), is abnormally expressed in diverse malignant tumors, regulated mRNA, miRNA, relevant target gene or protein through specific signal transduction pathways to function in mechanisms of proliferation, invasion and metastasis of tumor cells. HOTAIRM1 is closely related to the clinicopathology or molecular pathology and have shown great potential in therapy and predicting prognosis of patients.

Key words: long non-coding RNA, HOTAIRM1, tumors, regulatory effects

CLC Number:

R730

ZHAO Yu-qiao, SU Zhi-lei, CUI Yun-fu, GUAN Cang-hai, JIANG Xing-ming. Regulatory effects and mechanisms of HOTAIRM1 in malignant tumors[J]. Basic & Clinical Medicine, 2021, 41(2): 262-266.

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