Abstract: Based on the comprehensive analysis of characteristics of clinical trial MOOCs of high level, the article interpreted the importance of case-based teaching for scientific research education. Then we thought and planed accordingly for the construction of MOOCs of Peking Union Medical College Hospital (PUMCH) to improve the brand building of PUMCH, strengthen exchanges among medical education institutions of international high level and response to the strong demand of online-learning from clinician.

Key words: PUMCH, clinical trial, MOOCs, case-based teaching