Abstract: The human gut contains a lot of microbiota, which constitutes a complex and important ecosystem and influences human physiological function. The intestinal mucosa is the important barrier for our body. The connection between the intestinal micriecology and the intestinal mucosa keep our body stabilized. Once the intestinal micro ecology is destructed, intestinal flora will be imbalanced and will cause intestinal mucosa damaged by other ways. Eventually, harmful pathogenic bacteria will invade human gut.

Key words: gut microbiota, intestinal microecology, intestinal mucosa, intestinal mucosal barrier.