Abstract: In the context of medical higher education and information depth integration, we carry out the "pathology" blended-teaching based on the Blackboard. The " precision medicine " philosophy as a guide, in accordance with the different characteristics of students individual teaching design. At the same time, we cultivate students comprehensive thinking mode and guide students through the analysis of the clinical data to integrate medical disciplines related knowledge through blended learning. And establish evaluation scheme of students, a comprehensive analysis of the use of big data of student assessment results. In order to promote the student individual as the center of the "precision teaching" information technology development process.

Key words: Internet +, precision medicine, curriculum integration, precise teaching