Abstract: Objective To study IgAN patients associated to HIV infection, clinical, pathological and treatment. Method The patients came from PUMC hospital, who hospitalized between 2002 and 2012, diagnosed as HIV associated with IgAN by renal biopsy. Results 4 HIV patients had proteinuria, SCr level were normal. Renal biopsy showed IgAN. All 4 patients received HAART，3 patients receieved ACEI/ARB treatment， 1 patient proteinuria decreased, then 2 patients were given prednisone treatment，HIV virus copies were not increased. Conclusion HIV infection could be associated with many types of renal diseases including IgAN. Renal biopsy could be necessary if diagnosis was not confirmed.

Key words: HIV infection, IgAN, treatment