Basic & Clinical Medicine ›› 2025, Vol. 45 ›› Issue (12): 1648-1652.doi: 10.16352/j.issn.1001-6325.2025.12.1648

• Case Reports • Previous Articles     Next Articles

Advanced colon cancer with bladder metastasis complicated by disseminated intravascular coagulation: a case report

LI Siyuan1, DONG Jie2*   

  1. 1. Department of Hematology; 2. Department of Urology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730, China
  • Received:2025-06-23 Revised:2025-09-19 Online:2025-12-05 Published:2025-11-25
  • Contact: *pumchdongjie@163.com

Abstract: Objective To investigate the management strategies for disseminated intravascular coagulation (DIC) secondary to advanced malignancies. Methods Clinical data of an elderly male with advanced colon cancer, multiple bladder/pelvic wall metastases, and secondary DIC was collected and analysed. Diagnostic and therapeutic processes were systematically evaluated. Results The patient successfully underwent surgery to relieve urinary tract obstruction after transfusion support. Despite subsequent correction of coagulopathy with supportive care and anticoagulation, the prognosis remained poor due to tumor progression and DIC decompensation. Conclusions The management of malignancy-complicated DIC requires dynamic assessment of coagulation status. Temperate anticoagulation might aid in DIC control even in the presence of bleeding risk.

Key words: colon cancer, bladder metastasis, disseminated intravascular coagulation

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