Monitoring effect of Aspergillus fumigatus specific IgG for recurrence of allergic bronchopulmonary aspergillosis

doi:10.16352/j.issn.1001-6325.2023.08.1280

Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (8): 1280-1283.doi: 10.16352/j.issn.1001-6325.2023.08.1280

• Clinical Sciences • Previous Articles Next Articles

Monitoring effect of Aspergillus fumigatus specific IgG for recurrence of allergic bronchopulmonary aspergillosis

TANG Rui^1#, LEI Shubin^2#, SUN Jinlyu^1*

1. Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment of Allergic Disease, National Clinical Research Center for Dermatologic and Immunologic Diseases(NCRC-DID),Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730;
2. Eight-year Medical Doctor Program, CAMS & PUMC, Beijing 100730, China

Received:2022-05-07 Revised:2022-09-29 Online:2023-08-05 Published:2023-07-26
Contact: ^*18611382050@163.com

Abstract

Abstract: Objective To investigate serological monitoring indicator of the recurrence of allergic broncho-pulmonary aspergillosis (ABPA). Methods The follow-up records of 18 outpatients in Peking Union Medical College Hospital from June 2001 to September 2021 were collected and analyzed statistically. Results In total, 68 records of 18 patients had been analyzed. Three models were conducted, model 1 included serological Aspergillus fumigatus specific IgG(Gm3) level as a single variant, model 2 added gender and age based on model 1, and model 3 added Aspergillus fumigatus specific IgE level and the count of white blood cells based on model 1. Serological Gm3 level was an independent risk factor in all 3 models. Conclusions Serological Gm3 level is potential serological marker used in monitoring the recurrence of ABPA.

Key words: allergic bronchopulmonary aspergillosis, Aspergillus fumigatus specific IgG, monitoring factor, recurrence

CLC Number:

R563.9

TANG Rui, LEI Shubin, SUN Jinlyu. Monitoring effect of Aspergillus fumigatus specific IgG for recurrence of allergic bronchopulmonary aspergillosis[J]. Basic & Clinical Medicine, 2023, 43(8): 1280-1283.

References 12

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Monitoring effect of Aspergillus fumigatus specific IgG for recurrence of allergic bronchopulmonary aspergillosis

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