Abstract: Objective To recommend strategies to strengthen management and supervision by leaders in research institute through investigating and understanding the current situation analyzing the challenges and barriers from the view angle of Organization Department. Methods A self-designed questionnaire was conducted to investigate the current situation, the challenges, the objects and methods, problems and strengthening strategy of management and supervision for team of leadership in the institute. The staff of research institutes engaged in the management and supervision of leading cadres were interviewed. Results There were 69.61% of the respondents considered that “scientific performance and fair assessment and evaluation of leader personel ” was the difficulty of management and supervision and 75.69% of the respondents considered that “strengthening the routine management and supervision of leading team members and implementing the supervision rules and regulations strictly” was the focus of management and supervision. The results also showed that 70.72% of the respondents considered that “superior supervision” was the most direct and effective supervision and 90.61% of the respondents considered that the “top leaders of the party and government” was the key objects of management and supervision. Conclusions Strengthening the management and supervision of leading team members of scientific research institutes will be implemented by establishing and perfecting the management and supervision system, strengthening the education and training of, clarifying the key management and supervision objects and innovative management / supervision methods.

Key words: Organization Department, medical research institutes, leaders, management supervision