The interaction of TGF-β/Smads signal transduction pathway and microRNA

Abstract

Abstract: TGF-β/Smads pathway have a wide range of interactions with MicroRNAs. It has important roles in the control of gene epigenetics, transcription and post-transcriptional processing of MicroRNAs; while also from the post-transcriptional level MicroRNAs inhibit TGF-β/Smads pathway related genes expression. They also have significant relationship with a variety of human diseases, including tissue fibrosis, scar healing and tumor.

Key words: TGF-β, Smads, microRNA, control

CLC Number:

Feng Zhao ping shi. The interaction of TGF-β/Smads signal transduction pathway and microRNA[J]. Basic & Clinical Medicine, 2013, 33(11): 1426-1429.

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The interaction of TGF-β/Smads signal transduction pathway and microRNA

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