基础医学与临床 ›› 2024, Vol. 44 ›› Issue (3): 403-407.doi: 10.16352/j.issn.1001-6325.2024.03.0403

• 短篇综述 • 上一篇    下一篇

NMES1基因在恶性肿瘤中作用的研究进展

吴玉红, 喻才元, 叶石才*   

  1. 广东医科大学附属医院 消化内科,广东 湛江 524000
  • 收稿日期:2023-09-15 修回日期:2023-12-27 出版日期:2024-03-05 发布日期:2024-02-22
  • 通讯作者: *:caizi@126.com

Research progress on the role of NMES1 gene in malignant tumors

WU Yuhong, YU Caiyuan, YE Shicai*   

  1. Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, China
  • Received:2023-09-15 Revised:2023-12-27 Online:2024-03-05 Published:2024-02-22
  • Contact: *:caizi@126.com

摘要: 食管正常黏膜特异性1基因(NMES1)被认为是一个抑癌基因,在多种恶性肿瘤中的表达水平显著降低。NMES1可以影响肿瘤细胞的增殖、凋亡和迁移等多种细胞生物学行为,为寻找恶性肿瘤早期标志物或治疗靶点提供新的方向及策略,有助于评估患者的疾病进程和预后。

关键词: NMES1, 恶性肿瘤, 细胞生物学行为

Abstract: The normal esophageal mucosa specific 1 gene (NMES1) is considered as a tumor suppressor gene which significantly reduces expression of various malignant tumors. The NMES1 can affect various cellular biological behaviors such as proliferation, apoptosis and migration of tumor cells. These findings provide new strategies for searching early biomarkers or therapeutic targets of malignant tumors and support the evaluation of disease progression and prognosis.

Key words: NMES1, malignant tumor, cellular biological behavior

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