| [1] |
Jaye M,Lynch KJ,Krawiec J, et al.A novel endothelial-derived lipase that modulates HDL metabolism[J].Nat Genet,1999,2:424-428.
|
| [2] |
Liu C,Dhindsa D,Almuwaqqat Z, et al.Association between high-density lipoprotein cholesterol levels and adverse cardiovascular outcomes in high-risk populations[J].JAMA Cardiol,2022,7:672-680.
|
| [3] |
Yang S,Yin RX,Miao L, et al.LIPG SNPs, their haplotypes and gene-environment interactions on serum lipid levels[J].Lipids Health Dis,2019,18:10.doi:10.1186/s12944-018-0942-y.
|
| [4] |
Nagao M,Miyashita K,Mori K, et al.Serum concentration of full-length-and carboxy-terminal fragments of endothelial lipase predicts future cardiovascular risks in patients with coronary artery disease[J].J Clin Lipidol,2019,13:839-846.
|
| [5] |
其布热,周红,董莉.内皮酯酶基因多态性与冠心病的关系研究[J].临床和实验医学杂志,2019,18:699-703.
|
| [6] |
Schilcher I,Kern S,Hrzenjak A, et al.Impact of endothelial lipase on cholesterol efflux capacity of serum and high-density lipoprotein[J].Sci Rep,2017,7:12485.doi:10.1038/s41598-017-12882-7.
|
| [7] |
Khetarpal SA,Vitali C,Levin MG, et al.Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins[J].PLoS Genet,2021,17:e1009802.doi:10.1371/journal.pgen.1009802.
|
| [8] |
Wu L,Soundarapandian MM,Castoreno AB, et al.LDL-cholesterol reduction by angptl3 inhibition in mice is dependent on endothelial lipase[J].Circ Res,2020,127:1112-1114.
|
| [9] |
Wang C,Nishijima K,Kitajima S, et al.Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits[J].Arterioscler Thromb Vasc Biol,2017,37:1282-1289.
|
| [10] |
Wu YE,Ma L,Zhang H, et al.Significant association between the endothelial lipase gene 584C/T polymorphism and coronary artery disease risk[J].Biosci Rep,2020,40.doi:10.1042/BSR20200027.
|
| [11] |
Schilcher I,Stadler JT,Lechleitner M, et al.Endothelial lipase modulates paraoxonase 1 content and arylesterase activity of HDL[J].Int J Mol Sci,2021,22.doi:10.3390/ijms22020719.
|
| [12] |
陈永宏,杨松,周建中.阿托伐他汀减轻肾性高血压大鼠血管重构[J].基础医学与临床,2010,30:383-388.
|
| [13] |
Trimarco V,Izzo R,Morisco C, et al.High HDL(high-density lipoprotein) cholesterol increases cardiovascular risk in hypertensive patients[J].Hypertension,2022,79:2355-2363.
|
| [14] |
Yue X Wu M,Jiang H, et al.Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways[J].Mole Med Reports,2016,14: 1979-1985.
|
| [15] |
Dalan AB,Toptaş B,Buǧra Z, et al.The effects of endothelial lipase gene (LIPG) variants on inflammation marker levels and atherosclerosis development[J].Mol Biol Rep,2013,40:5143-5149.
|
| [16] |
Cadenas C,Vosbeck S,Edlund K, et al.LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer[J].Int J Cancer,2019,145:901-915.
|
| [17] |
Nakajima H,Ishida T,Satomi-Kobayashi S, et al.Endothelial lipase modulates pressure overload-induced heart failure through alternative pathway for fatty acid uptake[J].Hypertension,2013,61:1002-1007.
|
| [18] |
Schilcher I,Ledinski G,Radulović S, et al.Endothelial lipase increases antioxidative capacity of high-density lipoprotein[J].Biochim Biophys Acta Mol Cell Biol Lipids,2019,1864:1363-1374.
|
| [19] |
Wan A,Rodrigues B.Endothelial cell-cardiomyocyte crosstalk in diabetic cardiomyopathy[J].Cardiovasc Res,2016,111:172-183.
|
| [20] |
Yan H,Niimi M,Wang C, et al.Endothelial lipase exerts its anti-atherogenic effect through increased catabolism of β-VLDLs[J].J Atheroscler Thromb,2021,28:157-168.
|
| [21] |
Kobayashi J.Which is the Best predictor for the develop-ment of atherosclerosis among circulating lipoprotein lipase, hepatic lipase, and endothelial lipase?[J].J Atheroscler Thromb,2019,26:758-759.
|
| [22] |
Yu X,Lu J,Li J, et al.Serum triglyceride lipase concentrations are independent risk factors for coronary artery disease and in-stent restenosis[J].J Atheroscler Thromb,2019,26:762-774.
|
| [23] |
Tora G,Kim SH,Pi Z, et al.Identification of reversible small molecule inhibitors of endothelial lipase (EL) that demonstrate HDL-C increase in vivo[J].J Med Chem,2020,63:1660-1670.
|
| [24] |
Johnson JA,Tora G,Pi Z, et al.Sulfonylated benzothia-zoles as inhibitors of endothelial lipase[J].ACS Med Chem Lett,2018,9:1263-1268.
|
| [25] |
Ruff CT,Koren MJ,Grimsby J, et al.LEGACY: phase 2a trial to evaluate the safety, pharmacokinetics, and pharmacodynamic effects of the anti-EL(endothelial lipase) antibody MEDI5884 in patients with stable coronary artery disease[J].Arterioscler Thromb Vasc Biol,2021,41:3005-3014.
|
| [26] |
Meng W,Adam LP,Behnia K, et al.Benzothiazole-based compounds as potent endothelial lipase inhibitors[J].Bioorg Med Chem Lett,2019,29:126673.doi:10.1016/j.bmcl.2019.126673.
|
